Line·Whale
Upcoming
MLBMMA
NHL
Home/NFL/Detroit Lions vs Buffalo Bills

Detroit Lions vs Buffalo Bills odds and betting data

This is the NFL event page for Detroit Lions vs Buffalo Bills. You can see and compare odds across different sportsbooks. The matchup is scheduled for Friday, September 18 at 12:15 AM UTC, and the odds tables below organize every available price by sportsbook, market, team, and outcome so you can quickly scan the best number before placing a bet.

Linewhale highlights the strongest current prices across 9 sportsbooks, including moneyline prices when available, spread points and prices, and over/under totals. Use this page to compare sportsbook odds, identify the best price for each side, review market differences, and open free line movement history for individual odds.

Free line movement for Detroit Lions vs Buffalo Bills

To see line movement for this event, use the odds table below and click a specific moneyline, spread, or total price. Linewhale will open a free line movement chart for the selected sportsbook and outcome for Detroit Lions vs Buffalo Bills, can review how that number has changed before you bet.

NFLFriday, Sep 18, 12:15 AM UTC
DLI
Detroit
Lions
Buffalo
Bills
BBI
vs
Win Probability
38%62%
Spread · Best Across Books
DRALions+3-110
DRABills-3-110
Total · Best Across Books
DRAOver+52.5-110
DRAUnder+52.5-110
Moneyline · Best Across Books
DRALions+136
DRABills-161

Moneyline· Pick the winner

Side
DDraftKings
FFanDuel
FFanatics Sportsbook
BBetMGM
BBovada
CCaesars Sportsbook
BBetRivers
Detroit Lions
Buffalo Bills

Spread· Detroit Lions +3 / Buffalo Bills -3

Side
DDraftKings
FFanDuel
FFanatics Sportsbook
BBetMGM
LLowVig.ag
BBovada
BBetRivers
BBetOnline.ag
Detroit Lions
+3
+3
+3
+3
+3
+3
+3
+3
Buffalo Bills
-3
-3
-3
-3
-3
-3
-3
-3

Spread· Detroit Lions +3.5 / Buffalo Bills -3.5

Side
CCaesars Sportsbook
Detroit Lions
+3.5
Buffalo Bills
-3.5

Total· Over / Under

Side
DDraftKings
FFanDuel
FFanatics Sportsbook
BBetMGM
LLowVig.ag
BBovada
CCaesars Sportsbook
BBetRivers
BBetOnline.ag
Over
52.5
Under
52.5

Detroit Lions vs Buffalo Bills betting odds overview

Compare NFL odds for Detroit Lions vs Buffalo Bills, scheduled for Friday, September 18 at 12:15 AM UTC. Linewhale tracks moneyline, spread, and total prices across major US sportsbooks so you can compare the best available number before placing a bet.

Best moneyline odds

Detroit Lions is listed at +160 on Caesars Sportsbook, while Buffalo Bills is listed at -161 on DraftKings.

Best spread odds

The best listed spread prices are Detroit Lions +3 at -105 on Fanatics Sportsbook and Buffalo Bills -3 at -105 on BetMGM.

Best total odds

The best over price is -110 on DraftKings; the best under price is -102 on FanDuel. The listed total is 52.5.

Odds can move quickly as sportsbooks adjust to injuries, lineup news, betting volume, and market-making books. Always confirm the final price at the sportsbook before submitting a wager.